The therapy used resembles hormone replacement regimens used to treat natal men with hypogonadism and most of the preparations are testosterone esters. It may, however, be eliminated nearly permanently with laser hair removalor permanently with electrolysis. Spider veins may appear or be more noticeable as a result. In spite of the induction of breast development, transgender women who undergo HRT do not have an increased risk of breast cancer. Endocr J ; A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women.
Exogenous testosterone is used in transgender men to induce virilization and suppress feminizing characteristics.
Estrogen levels do not rise for transgender men treated with testosterone therapy
In our clinical practice, we avoid daily doses higher than 50 mg of CA because of its potential metabolic side effects, including weight gain and high blood pressure. There is biologic evidence that may explain this. These have the ability to significantly impact sexual functioning, either directly or indirectly through the various side effects, such as cerebrovascular disorders, obesity, and mood fluctuations. These guidelines are mostly based on clinical experience from experts in the field. Hormone therapy may even have a positive effect on physiologic stress as well. Current treatment guidelines for transgender men using testosterone therapy suggest that there is a potential need for estrogen lowering strategies, including the removal of the uterus or ovaries, to lower the reproductive health risks.
Whatever route an individual and their doctor choose to take, it is important to consider both the medical risks of hormone therapy as well as the psychological needs of the patient. Two pellets should be inserted for every 25 mg of parenteral testosterone needed weekly. Retrieved 31 July As a result, the updated guidelines do not require this step, and instead, the societies recommend that patients transition socially and with medical therapy at the same time 78. Normal value for premenopausal women at the follicular phase of the menstrual cycle: The administration of exogenous virilizing hormones is considered medically necessary for many transgender individuals 7. This prolonged suppression is thought to result from a direct effect of estrogens on the Leydig cells.